(2S)-N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-2-phenylglycine tert-butyl ester CAS NO.208255-80-5

Because of advanced technique, our company can produce a lot of DAPT.We are sure our price is the lowest and our quality is the DAPT…

Because of advanced technique, our company can produce a lot of DAPT.We are sure our price is the lowest and our quality is the   DAPT, a cell-permeable dipeptide, inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate1. Since the Notch pathway is involved in the development of both the nervous system and pancreas, DAPT may be useful in modulating Notch activity in embryonic stem cell differentiation studies2. DAPT has been shown to dose-dependently decrease amyloid-β (A-β) levels via inhibition of γ-secretase in both plasma and cerebral spinal fluid3. Since amyloid-β (A-β) containing senile plaques are characteristic in Alzheimer’s disease, DAPT may be useful in studies evaluating potential treatments for that diseas